Table S1 from RGN6024 Is a Brain-Penetrant, Small-Molecule Tubulin Destabilizer for the Treatment of Glioblastoma

Key Points

• MAIN FINDING: RGN6024 acts as a brain-penetrant small-molecule tubulin destabilizer targeting glioblastoma.
• KEY EVIDENCE: Experimental data highlights improved cancer cell viability when treated with RGN6024 compared to controls.
• APPROACH: The study evaluated the effects of RGN6024 and RGN3067 on multiple glioblastoma cell lines.
• SIGNIFICANCE: These findings propose a potential new treatment for glioblastoma, enhancing therapeutic options for patients.