Supplementary figure S1 from Tumor Cell–Intrinsic Decr2 Regulates Ferroptosis and Immunotherapy Efficacy
Key Points
MAIN FINDING: Decr2 expression modulates the efficacy of immunotherapy by affecting tumor cell resistance.
KEY EVIDENCE: Tumor cell models with Decr2 knockdown demonstrated resistance to CD8+ T cell killing in vitro.
APPROACH: The study utilized transplantable tumor cell models and examined the impact of Decr2 expression.
SIGNIFICANCE: Understanding Decr2's role helps in improving immunotherapy strategies for treating tumors.
Abstract
Supplementary Figure S1. Decr2 allele and expression in transplantable tumor cell models and Decr2 knockdown tumor cells were resistant to CD8+ T cell killing in vitro.