Supplementary figure S11 from Tumor Cell–Intrinsic Decr2 Regulates Ferroptosis and Immunotherapy Efficacy

Key Points

• Knockdown of decr2 in tumors results in resistance to ferroptosis, indicating its role in tumor biology.
• This finding highlights the connection between decr2 and the effectiveness of immunotherapy treatments.
• The study utilized a knockdown approach to assess tumor responses to induced ferroptosis.
• Understanding decr2's role may inform strategies to enhance immunotherapy outcomes in resistant tumors.