With the help of modern medical technology, various neoplastic and nonneoplastic lesions are getting diagnosed in the subclinical stage. Also, by lowering the threshold of disease definition, a large number of at-risk individuals get reclassified to the disease category. Quite often, these conditions remain harmless throughout a lifetime. Overzealous management in these settings becomes therefore unnecessary and results in various treatment-related adverse effects.
Ananda Datta (Tue,) studied this question.
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