Bio-analytical chemistry plays a crucial role in the quantitative measurement of analytes in biological matrices, supporting drug development, therapeutic monitoring, and disease diagnosis. This field employs a range of methodologies, including chromatography (HPLC, GC), mass spectrometry (LC-MS/MS), and electrophoresis (CE). Ensuring the accuracy and reliability of these methods requires rigorous validation, encompassing assessments of specificity, sensitivity, precision, and stability. As bio-analytical chemistry continues to evolve, advancements in miniaturization, high-throughput analysis, and omics technologies (study large sets of biological molecules) are enhancing its capabilities. The development of precise and dependable analytical methods is essential for driving biomedical research and improving healthcare outcomes. By integrating cutting-edge techniques with robust validation protocols, bio-analytical chemistry remains a vital discipline in the pursuit of scientific and medical advancements.
Mohamad et al. (Tue,) studied this question.
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