Background: Pancreatoduodenectomy (PD) has one of the strongest volume-outcome relationships in all of surgery. It is unclear whether this relationship has a plateau for a certain volume. If so, merging two high-volume centers would not lead to further improve patient outcomes. However, data are inappropriate as current studies on volume-outcome relationships are based on a relatively low annual center volumes of 10-50 PDs.
Rompen et al. (2025) studied this question.
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