Introduction: Catecholamine-secreting adrenal tumors (pheochromocytoma/paraganglioma) are rare neoplasms causing paroxysmal hypertension, metabolic disturbances, and cardiomyopathy. Diagnosis relies on biochemical tests (plasma-free metanephrines) and imaging (CT/MRI). Definitive treatment involves tumor resection with perioperative hemodynamic control. Case summary: A 47-year-old female with no prior hypertension presented with chest pain, hypertensive crisis (180/100 mmHg), hyperglycemia, and metabolic acidosis. Elevated norepinephrine (312.33 pg/mL) and abdominal MRI confirmed a right adrenal tumor (22×22×20 mm). A surgical resection was performed. Postoperatively, blood pressure normalized, and cardiac function improved (EF increased from 47% to 70% at the 2-month follow-up). Conclusion: Catecholamine-secreting tumors may induce severe cardiomyopathy even without a hypertension history. Early diagnosis and prompt surgery are critical for cardiac recovery and preventing complications.
Nguyen et al. (Thu,) studied this question.