Antioxidants have the effect of delaying the aging process by removing active oxygen or inhibiting its production. It refers to a compound that inhibits oxidation reactions or reacts with active oxygen to stabilize them, and its main mechanism is to supply electrons to active oxygen to stop the radical chain reaction, and to inhibit the preperoxide reaction in which metal ions generate active oxygen, thereby lowering the expression of inflammatory factors and indirectly reducing active oxygen. These antioxidants can be divided into natural and synthetic materials. Recently, the discovery of natural antioxidants has been actively progressing, and this study aimed to analyze the trend. As a result, various studies have been conducted on the separation, purification, efficacy evaluation, and safety assurance of antioxidants such as 6-gingerol, 6-chrysophanol, Carnosic acid, Asiaticoside, Resveratrol, Quinic acid, Morin, Mangiferin, Ginsenoside Rg1, (-)-Epigallocatechin Gallate, Quercetin, and Luteolin from natural medicines, vegetables, and fruits that we can easily come across around us. These studies were mainly conducted as a step for application to the pharmaceutical, food, and cosmetics industries, and the mechanism could be analyzed through this study. The direction for future research is to ensure that antioxidants are not oxidized in the product and can be used stably during the distribution period or use period. In addition, analyzing the mechanism of an effective formulation delivery system that is well delivered to the body through ingestion or application to the skin and sufficiently maintains antioxidant efficacy is also a future research direction.
Bo-Ae Kim (Thu,) studied this question.