Psychotic disorders are common in individuals with epilepsy, with a prevalence significantly higher than in the general population. These disorders can present in various forms, depending on their timing in relation to seizures and level of consciousness. Despite their clinical specificity, epileptic psychoses are not recognized as distinct entities in current psychiatric classifications, complicating diagnosis and management. This article presents the case of a 23-year-old man with nocturnal seizures and persistent psychotic symptoms (auditory hallucinations and persecutory delusions) unresponsive to antiepileptic treatment. EEG confirmed fronto-temporal epilepsy. The patient was ultimately diagnosed with an interictal schizophrenia-like psychosis associated with epilepsy. Combined treatment with antiepileptic and antipsychotic medication led to clinical improvement. This case highlights the complexity of diagnosing psychosis in epilepsy and underscores the need for close collaboration between neurologists and psychiatrists to ensure appropriate care. A better understanding of this comorbidity is crucial for improving outcomes in affected patients.
Korchi et al. (Mon,) studied this question.
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