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September 10, 2025

A Review on Pharmaceutical Cocrystals

Key Points

Pharmaceutical cocrystals enhance solubility and stability of drugs, improving therapeutic efficacy.
Cocrystals comprise an active pharmaceutical ingredient and another molecule in a defined ratio.
Preparation methods for cocrystals include cocrystallization techniques to optimize properties.
The review covers evaluation methods, physicochemical properties, and real-world applications.

Abstract

Pharmaceutical cocrystals are crystalline materials composed of two or more different molecules, at least one being an active pharmaceutical ingredient (API), in a fixed stoichiometric ratio, held together by non-covalent interactions.Cocrystal can be prepared by cocrystallization method. Thus it improves the performance of solubility,stability and dissolution profile.This review article gives an overview on Pharmaceutical cocrystal including preparation method, physicochemical properties, evaluation and applications

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Sameer et al. (Tue,) studied this question.

synapsesocial.com/papers/68c1afcd54b1d3bfb60e7d82 — DOI: https://doi.org/10.35629/4494-1004215223

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Authors

Samina Sameer

Shinta Babu Shinta Babu

Aparna P Aparna P

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A Review on Pharmaceutical Cocrystals

Key Points

Abstract

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Discussion

Cite this study

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Authors

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References and Citations

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