Purpose: Crystalline lens subluxation in children with Marfan syndrome often requires surgical correction to prevent amblyopia. Capsular anchor device (AssiAnchor, Hanita Lenses, Israel) enables the preservation of the capsular bag for the placement of a Posterior Chamber Intraocular Lens, maintaining natural anatomy and effective lens position. Setting: Department of Ophthalmology, Meir Medical Center, Kfar Saba, Israel. Design: Retrospective, consecutive case series. Methods: We collected data on pediatric patients with genetically or clinically confirmed Marfan syndrome who underwent lens extraction with IOL implantation and bag preservation using the AssiAnchor device. Results: A total of 10 eyes of 8 patients were included. Mean postoperative follow-up was 5.08 years (range 2-9.25 years). Average age at surgery was 6.9±3.3 years (range 2.8-13.75). The mean best-corrected visual acuity improved from 20/80 to 20/30 (p=0.01). Mean Absolute Error from the aimed refraction was -0.37±0.6 D (range -1.25 to 0.75 D). At the last follow-up, all IOLs were stable and central, with healthy conjunctival tissue over the sutures and flanges. Postoperative complications included glaucoma in 1 eye and IOL subluxation in 2 eyes of the same patient. Posterior capsular opacification occurred in 6 eyes, strabismus developed in one patient and resolved in two patients. Amblyopia was identified in 6 eyes (60%), comprising 5 mild cases and 1 moderate case. Conclusions: The capsular anchor device effectively managed lens subluxation in pediatric Marfan syndrome, providing long-term stabilization of the capsular bag and facilitated IOL implantation. Our findings demonstrate satisfactory visual and refractive outcomes with an acceptable rate of complications.
Yehezkeli et al. (Wed,) studied this question.