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This is a Literature Review study.

September 10, 2025

Gender Affirmation Research Is Not Gender Ideology Extremism, It Is Science

Key Points

Gender affirmation research is grounded in science, demonstrating its validity and importance in public health.
Evidence shows that gender affirmation positively impacts mental health and well-being among transgender individuals.
The analysis emphasizes the necessity of incorporating health equity principles in the understanding of gender identity.
Engagement in social research is essential to counter misinformation surrounding gender ideology and its implications.

Abstract

Gender Affirmation Research Is Not Gender Ideology Extremism, It Is Science Arjee J. Restar PhD, MPH, Kristi E. Gamarel PhD, EdM, and Don Operario PhD Affiliation Arjee J. Restar is with the Department of Social and Behavioral Science, Yale University School of Public Health, New Haven, CT. Kristi E. Gamarel is with the Department of Health Behavior and Health Equity, and the Institute for Social Research Population Studies Center, University of Michigan School of Public Health, Ann Arbor. Don Operario is with the Department of Behavioral, Social, and Health Education Sciences, Emory University Rollins School of Public Health, Atlanta, GA, when this article was written. CopyRightCorrespondence should be sent to Arjee Javellana Restar, Laboratory of Epidemiology and Public Health, 60 College St, New Haven, CT 06510 (e-mail: arjee.restar@yale.edu). Reprints can be ordered at http://www.ajph.org by clicking the "Reprints" link. CONTRIBUTORS A. J. Restar drafted the article. All authors contributed substantially to the conceptualization, analysis, and interpretation of the work; edited and reviewed the article; and approved of the final published version and agree to be accountable for all aspects of the work. https://doi.org/10.2105/AJPH.2025.308220 Accepted: June 13, 2025 Published Online: August 07, 2025

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