The Aspartate Aminotransferase-to-Platelet Ratio Index (APRI) is a non-invasive marker for liver brosis and cirrhosis, while the Child-Pugh (CP) score remains a gold standard for assessing disease severity and prognosis. This cross-sectional study on 66 cirrhotic patients evaluated the correlation between APRI and CP scores and their association with disease complications. The mean age of the cohort was 42.12 ± 8.40 years, with a male predominance (90.9%). The most common etiology was alcohol (69%), followed by hepatitis B (15%), hepatitis C (9%), MASLD (3%), autoimmune hepatitis (2%), and cryptogenic causes (2%). Ascites was absent in 19 patients, controlled in 33, and refractory in 14. Hepatic encephalopathy was absent in 23 patients, minimal in 32, and advanced in 11. CP classication revealed 27 patients in Class A, 35 in Class B, and 4 in Class C. A signicant positive correlation was found between APRI and CP scores (r = 0.495, p = 0.018). Patients with refractory ascites and advanced encephalopathy had higher mean APRI (3.36 ± 1.52 and 3.22 ± 1.4, respectively) and CP scores (12.00 ± 2.88 and 12.27 ± 1.56), indicating worsening liver function. These ndings suggest that APRI correlates well with CP scores and disease severity, underscoring its potential utility in the clinical assessment and prognostication of cirrhotic patients.
Sirasagi et al. (Tue,) studied this question.