What type of study is this?

This is a Experimental Study study.

September 17, 2025

An Open Source Motion-compensated Cardiac Diffusion Sequence Validated Across Different MRI Systems and Gradient Strengths

Key Points

Data acquisition for DWI and DTI was successful across all tested MRI systems, demonstrating versatility.
A systematic comparison highlighted differences in performance based on hardware specifications of MRI systems.
The open source approach allows widespread adoption and customization of the motion-compensated sequence.
This sequence promotes cross-vendor cooperation for multi-center studies, enhancing the consistency of cardiac diffusion MRI.

Abstract

Motivation: Cardiac Diffusion MRI results are difficult to compare due to variations in pulse sequence implementation. Goal(s): To develop an open source second order motion compensated cardiac diffusion sequence that can be applied reproducibly at different MRI systems. Approach: The sequence was developed using the open source sequence development platform Pulseq. Diffusion gradients optimized for different gradient strengths were tested on three volunteers across three different MRI systems. Results: DWI and DTI data could be acquired at all systems, and a systematic comparison revealed hardware-based performance differences. Impact: The sequence allows for consistent and comparable application of cardiac diffusion MRI at different MRI systems and field strengths enabling standardized multi-center studies and cross-vendor cooperation.

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Cite This Study

Arbes et al. (Tue,) studied this question.

synapsesocial.com/papers/68d4596631b076d99fa5c16f https://doi.org/https://doi.org/10.58530/2025/3055

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