What type of study is this?

This is a Quantitative Study study.

September 17, 2025

Whole heart diffusion tensor CMR using commercial ultrahigh performance whole body gradients

Key Points

Whole heart data was acquired in under 25 minutes, revealing critical microstructural variations across the myocardium.
Microstructural parameters showed systematic differences, highlighting the potential for improved cardiac assessment.
Motion compensated spin echo acquisitions were utilized with ultrahigh strength gradients to achieve diagnostics.
Innovative methodology enables noninvasive evaluation of localized pathological changes in cardiac microstructure.

Abstract

Motivation: Efficient whole heart noninvasive assessment of the cardiac microstructure has great prognostic and diagnostic potential, but current techniques are typically limited to sparsely distributed slices. Goal(s): Demonstrate whole heart diffusion tensor cardiovascular magnetic resonance (DT-CMR) in a clinically feasible scan time. Approach: Motion compensated spin echo (MCSE) acquisitions were performed with interleaved slice imaging and 2D RF pulses using a whole body ultrahigh strength gradient system in 20 healthy volunteers Results: Whole heart data was acquired in <25minutes demonstrating systematic differences in microstructural parameters across the LV myocardium. Impact: Ultrahigh strength gradient enabled whole heart DT-CMR will enable assessment of pathological localised changes in cardiac microstructure.

Bookmark

Whole heart diffusion tensor CMR using commercial ultrahigh performance whole body gradients

Key Points

Abstract

Cite This Study

Also Consider

Also Consider