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This is a Quantitative Study study.

September 17, 2025

Image quality assessment of multi-shot echo-planar diffusion weighted imaging for in vivo breast cancer screening

Key Points

High-quality diffusion weighted imaging can enhance breast cancer detection, and varying shot counts presents unique challenges.
Two-shot and six-shot sequences were assessed for image quality in nearly 200 women at high risk, highlighting the impact of b-values.
Evaluation by three raters revealed the severity of image artifacts, which could affect the usability of multi-shot imaging.
The findings may inform future clinical practices regarding the implementation of robust image quality techniques.

Abstract

Motivation: High b-value multi-shot echo-planar imaging (MS-EPI) diffusion weighted imaging (DWI) offers reduced distortion, high resolution, and high contrast that is promising for breast cancer screening. Improvements to reconstruction robustness are enabling use of higher b-values and higher shot counts. Goal(s): To assess breast MS-EPI DWI image quality versus number of shots and b-value across many exams. Approach: Two-shot (clinical) and six-shot (research) MS-EPI DWI sequences with different b-values will be used to screen approximately 200 women at high risk for breast cancer. Three raters will evaluate image artifact severity. Average ratings will be calculated for each sequence/b-value. Impact: Multi-shot DWI EPI can offer efficient, non-contrast enhanced breast cancer screening, but may suffer from artifacts that make images unusable. Evaluating the robustness of multi-shot DWI EPI will direct future efforts to translate these sequences for widespread clinical use.

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Image quality assessment of multi-shot echo-planar diffusion weighted imaging for in vivo breast cancer screening

Key Points

Abstract

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