Pulmonary embolism (PE) is a life-threatening condition requiring early and accurate diagnosis. The Wells and Geneva scores, along with D-dimer testing, are key tools in assessment. However, the standard D-dimer cut-off of 0.5 mg/mL, while highly sensitive, has low specificity, leading to excessive imaging. This study examines whether modifying the D-dimer threshold can improve diagnostic efficiency and reduce unnecessary testing.
Abu-Shanab et al. (Fri,) studied this question.