Abstract Background: Prostate cancer is the most common type of cancer and the second highest cause of cancer death in the United States (U.S). The prostate cancer incidence and death rates in the U.S. are twice as high among Black men. To address this issue, the Medical University of South Carolina Hollings Cancer Center (MUSC HCC) developed the South Carolina Prostate Cancer Education and Navigation to Screening Program for African American Men (SC AMEN Program). This program includes patient navigators who help to overcome social drivers of health barriers that could prevent Black men from receiving prostate cancer screening. Participants are guided to a physician for an informed decision-making discussion about prostate cancer screening. Methods: The Program includes a one-hour evidence-based prostate cancer educational session. The pre-test survey assesses prostate cancer knowledge using the validated PROCASE scale which is administered again at post-test following the educational session. Each participant is navigated to a physician to discuss prostate cancer screening over the next three months. Results: The 556 participants included Black (98.6%), American Indian/Alaska Native (0.7%), and Native Hawaiian or Other Pacific Islander men (0.4%), with 2.7% reporting Hispanic/Latino ethnicity. The age range of the 556 participants was 40-69 years; 7.6% had less than a high school education, 36.2% completed high school, 18.5% completed some college, and 36.7% were college graduates. The total average (SD) pretest score was 6.7±1.6/10. The total average post-test score was 7.0±1.9/10. The total point increase from pre-test to post-test was 0.3 (p=0.002). Of the 556 SC AMEN Program participants, 77% completed a prostate cancer screening (n=217/39%) or have scheduled a screening appointment (n=209/38%). The remaining 23% continue to be navigated to a screening appointment. Conclusions: The SC AMEN Program was successful in increasing the participants’ knowledge of prostate cancer and their access to prostate cancer screening. Citation Format: Amber S. McCoy, Marvella E. Ford, Angela M. Malek, Melanie Slan, Claudia E. Lawton, Lee H. Moultrie, Kenneth Swaringer, I'Ayana Sanders, Adam Pressley, Ellen Gomez, Jessica zserai, Joan McLauren, pMina Platt, Phuong Le, Chloe Keeve, Joie Zabec, Marla Sagatelian, Benjamin Stone, Nicholas Shungu. The SC AMEN program: Testing a centralized patient navigation intervention for prostate cancer screening in Black men abstract. In: Proceedings of the 18th AACR Conference on the Science of Cancer Health Disparities; 2025 Sep 18-21; Baltimore, MD. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2025;34(9 Suppl):Abstract nr B083.
McCoy et al. (Thu,) studied this question.