September 19, 2025Open Access

Expression of Concern PirB restricts neuronal regeneration in developing rat brain following hypoxia‑ischemia

Key Points

Potential data issues were identified in the immunofluorescence images presented, suggesting scientific integrity concerns.
The overlapping data in the 'HIBD' and 'HIBD+anti PirB' panels indicates possible alterations in image presentation.
The editorial office continues its investigation into these anomalies related to neuronal regeneration assessment.
This expression of concern aims to alert readers to the ongoing investigation of the research integrity of this publication.

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the immunofluorescence images shown in Fig. 3, the 'HIBD' panel appeared to share an overlapping section of data with the adjoining 'HIBD+anti PirB' panel, albeit the data held in common appeared to have been vertically stretched in the latter panel. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. Molecular Medicine Reports 6: 339‑344, 2012; DOI: 10.3892/mmr.2012.907

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Wang et al. (Thu,) studied this question.

synapsesocial.com/papers/68d46fbd31b076d99fa699c5 https://doi.org/https://doi.org/10.3892/mmr.2025.13688

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