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October 1, 2025Open Access

A Rare Presentation of Paget’s Disease of Nipple in the Absence of any Underlying Ductal Malignancy - A Case Report

Key Points

Ulceration and distortion of the nipple-areolar complex were observed, indicating Paget's disease.
The patient, a 60-year-old woman, had no history of breast cancer or hormone therapy, which is unusual.
Examinations revealed no underlying ductal malignancy or palpable lumps in the breast.
This case highlights a rare presentation of Paget’s disease distinct from typical malignancy cases.

Abstract

A 60-year-old female with no personal or family history of breast cancer, menopausal without hormone replacement therapy, presented with ulceration of the left nipple areolar complex for 1 year. On examination, the nipple-areolar complex was completely distorted with an erythematous, desquamative lesion with circular pearly margins. There was no palpable lump and no axillary lymph nodes. The right breast and axilla were normal both on inspection and on palpation.

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