October 1, 2025Neural Regeneration Research0 citationsOpen Access

Beyond the Barrier: Targeting blood–brain interactions for neuroprotection and repair

AVAnddre O. ValdiviaUniversity of California, San Francisco CBC A BrandtUniversity of California, San Francisco MPMark A. PetersenUniversity of California, San Francisco

Key Points

Targeting the blood-brain barrier may significantly enhance neuroprotection and repair mechanisms.
The interaction of neuroprotective strategies with the blood-brain barrier is crucial for their effectiveness.
Emerging therapies suggest promising approaches for improving repair in neurological conditions.
Understanding blood-brain interactions opens new avenues for treatment in neurodegenerative diseases.

Abstract

Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA *Correspondence to: Mark A. Petersen, MD, email protected. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License (http://creativecommons.org/licenses/by-nc-sa/4.0/), which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

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