Organofluorine compounds play a vital role across diverse sectors—from medicine and agriculture to materials science and imaging technologies. Their widespread use is made possible by continuous advances in synthetic methods, enabling access to both established and emerging fluorinated motifs; recent developments are covered in the Science of Synthesis volumes on Modern Strategies in Organofluorine Chemistry, edited by Jean-François Paquin. In this webinar, Tatiana Besset and Kevin Lam will share perspectives on recent developments in the field, highlighting evolving strategies and challenges in the synthesis of fluorinated molecules. The session will offer a broad overview of current trends and future directions in organofluorine chemistry. Unveiling Routes to Fluorinated Molecules Organofluorine chemistry is a fascinating research field in rapid expansion. Beyond the strong interest that represent fluorinated molecules in materials science, pharmaceuticals, agrochemicals, and modern drug design, innovation is still required to push further the boundaries of knowledge in this appealing research field and achieve new synthetic challenges. By combining homogeneous catalysis with emergent fluorinated groups, our group has developed innovative synthetic methods to access high-added-value organofluorinated molecules. This talk will provide an overview of our journey in this research field. Your Chemistry has got Potential: Fluorination reactions without the “bang” Chemistry thrives on highly reactive intermediates - remarkable tools for building complex molecules. But one might ask: shouldn't their synthesis involve fewer risks than a special life insurance policy? Synthetic organic electrochemistry, which has its roots in the pioneering work of Faraday and Kolbe on the electrolysis of aliphatic carboxylic acids, has become a powerful tool for sustainable chemical synthesis. Despite numerous successful industrial applications, its wider potential remains under-exploited. However, the increasing demand for greener, safer and more cost-effective synthetic methods has spurred the development of innovative electrosynthetic techniques. In this talk, we will review novel, safe, green and economically viable electrosynthetic methods for the preparation of highly reactive organic intermediates, including some rarely studied fluorinated functional groups. These methods significantly reduce the inherent risks associated with traditional synthetic approaches while improving efficiency and sustainability. We will also highlight the scalability of these processes through flow electrosynthesis.
A Mon, study studied this question.