Key points are not available for this paper at this time.
Bicyclo3.3.0octanes represent crucial structural motifs found in various bioactive natural compounds. In this study, we present the first metal‐free formal 3 + 2 cycloadditions of alkyne‐tethered cyclopropyl ketones via pyridine‐boryl radical catalysis, affording bicyclo3.3.0octanes with high efficiency and broad substrate scope. This reaction features the generation of ketyl radical by pyridine‐boryl radical and a consecutive 5‐exo‐dig and 5‐exo‐trig radical cascade process.
Hua et al. (Fri,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: