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Invasive group A streptococcal (GAS) disease, although rare, has a high mortality and morbidity rate, making early recognition and treatment crucial. Toxic shock syndrome (TSS) and necrotizing fasciitis are the most feared complications and require comprehensive, multidisciplinary treatment. In addition to appropriate support and resuscitation, patient management should include empirical broad-spectrum antibiotic therapy covering gram-negative bacteria, methicillin-resistant
Mendes et al. (Wed,) studied this question.
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