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Differentiating fibrosis and inflammation is vital important clinical distinction in patients with chronic liver disease (CLD). Liver histopathology is the worldwide reference standard for staging fibrosis and inflammation. Therefore, there is urgent need to develop non-invasive and low risk methods for staging liver fibrosis and inflammation. Current researches has been demonstrated that three-dimensional MRE allows showed higher diagnosis accuracy for staging liver fibrosis even inflammation than 2D MRE. Here, we prospectively evaluate the diagnosis efficacy of the parameters 3D MRE-derived for staging liver fibrosis and grade of inflammation in real clinical situations.
Wang et al. (Wed,) studied this question.