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Atypical high-grade glioma (HGG) (with no or little necrosis) and primary central nervous system lymphoma (PCNSL) are difficult to distinguish in routine MR images but their treatment strategies are totally different. Therefore, it’s important to distinguish between them before treatment. This study aimed to investigate the diagnostic efficiency of quantitative analysis based on mean apparent propagator-MRI in discriminating atypical HGG from PCNSL. Through quantitative analysis of MAP parameters, we found that MAP-MRI performed well in differentiating between atypical HGG and PCNSL.
Gao et al. (Wed,) studied this question.