Highly accelerated 3D hyperpolarized MRI at ultra-high fields using Seiffert Spirals

Isotropic 3D imaging of hyperpolarized media is generally challenging due to the extremely limited lifetime of the hyperpolarized phase. Fortunately, images of hyperpolarized media are often intrinsically sparse, resulting in an excellent precondition for non-linear reconstruction techniques such as Compressed Sensing. To preserve this condition, a 3D Seiffert Spiral trajectory was implemented at 11. 7 T, yielding low-coherent sampling properties for an arbitrary number of excitations, until depletion of the hyperpolarized signal. We show that qualitative images with a resolution of <500 m can be reconstructed from continuous data that was acquired in less than one second.