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MR elastography (MRE) can noninvasively detect liver fibrosis based on elevated stiffness values. However, a complete MRE scan is time-consuming and typically extends over multiple breath-holds. Therefore, a multi-shot gradient echo sequence with spiral readout was developed to provide full two-dimensional elastograms of the liver in less than one second. The new sequence can be used as an MRE navigator to provide immediate feedback on wave penetration and data consistency for parameter optimization prior to running full multi-dimensional MRE. Moreover, the method can be used to rapidly track potential changes in liver stiffness such as those induced by respiration.
Anders et al. (Wed,) studied this question.