Bacteriophages for the Treatment of Resistant Bacterial Infectious Diseases

Bacteriophages, or phages, are viruses that specifically infect bacterial cells and kill them. They have shown potential applications in medicine, agriculture, and biotechnology. Bacteriophages were discovered almost a century ago but were discontinued due to the emergence of antibiotics. In recent decades, due to increasing antimicrobial resistance, bacteriophages have been gaining renewed attention for the treatment of bacterial infections. Phage therapy offers a targeted and potentially sustainable alternative to antibiotics, with the ability to evolve alongside bacterial pathogens. This review provides an overview of the several aspects of bacteriophages including action, formulations, advantages and challenges for the treatment of bacterial infections.