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This study aims to optimize the extraction conditions of Ultrasonic-Assisted Extraction (UAE) on the extraction of phenolic compound and antioxidant activity of Citrus Hystrix (C. Hystrix) peel. The experimental design was carried out using Face Centered Central Composite Design. A total of 20 sets of different combination experiment designs were generated from 3 parameters; temperature (30-50°C), time (20-40 min), and raw material to the solvent ratio (1:30-1:70). The highest yield of total phenolic compounds was 4.36 mg/g with the optimize extraction condition of , 30 min extraction time and 1:50 raw material to the solvent ratio. The result of this study indicates that the phenolic compounds extracted from C. Hystrix peel could have the potential to be used for pharmaceutical and food applications.
Keat et al. (Sun,) studied this question.
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