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Sleep is key to health maintenance. Adolescents with T1D are at increased risk for sleep disruptions and shorter sleep duration. We examined differences between biological genders in sleep, glycemia and HRQOL outcomes for youth aged 11-17 yes with T1D. 70 youth (mean 14.5±1.8 yrs, 51% female, 76% Non-Hispanic White) participated in an observational study. Actigraphy data (sleep duration, sleep efficiency, sleep onset latency, wake after sleep onset) and glycemic data from CGM (TIR (70-180mg/dL), time hyperglycemic (180mg/dL), time hypoglycemic (70mg/dL)) were collected for 1-week, followed by self-report surveys (PROMIS, Sleep-Related Disordered Breathing SRDB, Fear of Hypoglycemia, Morningness/Eveningness). No significant gender differences were found for demographics, actigraphic sleep, or glycemic outcomes. Statistically significant differences were found for psychological stress (p=0.01), anxiety (p=0.03), depressive symptoms (p=0.01), sleep-related impairment (p=0.03), and SRDB (p=0.03) with females reporting poorer outcomes (Table). This study highlights gender differences in self-reported sleep and HRQOL among adolescents with T1D. Interventions to address poor sleep and psychological distress may benefit from a gender-specific lens. Further research is needed to elucidate gender differences and examine ways to improve sleep and glycemia for all adolescents. Disclosure E. Fivekiller: None. C. Sakamoto: None. K. Taylor: None. L. Pyle: None. L.J. Meltzer: Consultant; Egetis Therapeutics, Harmony Biosciences, Zepp Health. R. Wadwa: Research Support; Dexcom, Inc. Other Relationship; Dexcom, Inc. Research Support; Eli Lilly and Company. Advisory Panel; Eli Lilly and Company, Provention Bio, Inc. Research Support; Tandem Diabetes Care, Inc. Other Relationship; Eli Lilly and Company. E.C. Cobry: Advisory Panel; Dexcom, Inc. Other Relationship; Dexcom, Inc. Funding JDRF (5-ECR-2022-1179-A-N)
Fivekiller et al. (Fri,) studied this question.