Effect of breast tissue density on cell-free orphan non-coding RNAs secreted by breast cancers.

3065 Background: Early detection of breast cancer is crucial for improved patient outcomes but cannot always be achieved through mammography for the more than 40% of women with dense breast tissue (BI-RADS C t=-0.59, p=0.56) nor in oncRNA score (mean 0.496 vs 0.554 in fatty vs. dense tissue, MW p=0.42; t=-0.79, p=0.43) between breast density groups. Conclusions: Taken together, our results indicate that unlike mammograms, the use of oncRNAs for detecting breast cancer are not influenced by breast density. Further research will utilize oncRNA score in determining breast cancer early detection in women with dense breast tissue.