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Background: Urinary tract infections (UTIs) are considered one of the most common infectious diseases, affecting most people of all age. Objectives: This study was conducted to determine the types of common bacteria causing UTIs and to measure the sensitivity of antibiotics to different bacteria. Materials and Methods: The current study included 208 of young group patients (aged 18 - 50 years) clinically suspected of having a UTIs. Out of 208 samples, the culture results showed that only 100 samples were positive for the presence of significant bacteria. Samples (midstream urine) were collected in a sterile tube, and significant results were shown for the isolated bacteria on selective media, identified by the VITEK-2 system. Then the Kirby-Bauer method was used to perform antibiotic susceptibility testing according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: The most common bacteria identified included; Escherichia coli (68.3%), Staphylococcus aureus (7.8%), Enterococcus faecalis (6.7%), Klebsiella pneumoniae (5.8%), (3.8%) for both Pseudomonas aeruginosa and Staphylococcus saprophyticus, While Streptococcus agalactiae accounted for (1.9%), Proteus mirabillus and Serratia marcescens (0.9%) for all of them. Moreover, there was mixed bacterial growth. Results revealed E. coli was sensitive to Imipenem, Ciprofloxacin and resistant to Tobramycin and Amikacin. Meanwhile, K. pneumoniae was completely sensitive to Imipenem and Ciprofloxacin with utterly resistant to Piperacillin. P. aeruginosae was sensitive to Imipenem, Meropenem and resistant to Azithromycin, Tobramycin, Ceftriaxone and levofloxacin. Whereas, S.aureus was sensitive to Ciprofloxacin and Levofloxacin and resistant to Trimethoprim and Azithromycin, E. faecalis was sensitive to Vancomycin with resistant to Azithromycin and Ciprofloxacin. Conclusions: The study concluded that females are more susceptible to UTIs than to males. In addition, females with UTIs tend to be younger than males. E. coli is the most common isolate among bacteria that cause UTIs. Study revealed that Imipenem remains the most potent treatment for inhibiting most types of bacteria causing UTIs, in addition, Meropenem, Ciprofloxacin, and Levofloxacin can be considered a potential treatment option.
Kamel et al. (Thu,) studied this question.