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Introduction Type-2 biologics allow for successful treatment of patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP). Eosinophils have been established as a reliable biomarker of type-2 disease and enable the differentiation of inflammatory patterns in CRSwNP. Aim of this study was to evaluate, whether peripheral blood eosinophilia before initiation of therapy with type-2 biologics allows assesment of response to treatment in patients with CRSwNP.
Kotz et al. (Fri,) studied this question.