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Acromegaly, characterized by excessive growth hormone secretion often due to pituitary adenomas, presents diagnostic and therapeutic challenges, particularly when associated with giant invasive tumors. We present a case of a 26-year-old male with progressive visual impairment, headaches, and systemic symptoms indicative of acromegaly. Physical examination revealed classic features of acromegaly along with neurological deficits. Diagnostic work-up confirmed the presence of a giant invasive pituitary adenoma, highlighting the importance of clinical, radiological, and biochemical evaluation in diagnosis. Despite surgical intervention, residual tumor remained, necessitating adjunctive medical therapy. Management involved a multidisciplinary approach, incorporating surgery, pharmacotherapy, and potentially radiotherapy. This case underscores the complexities of managing acromegaly with giant adenomas, emphasizing the importance of early recognition and individualized treatment strategies to optimize outcomes.
Ismail et al. (Tue,) studied this question.
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