Mp18-01 Increased Provoked Bladder Compliance Associated With High Urgency Bother in a Subset of Women ≥50 Years Old Using Ultrasound Urodynamics

You have accessJournal of UrologyImaging/Uroradiology I (MP18)1 May 2024MP18-01 INCREASED PROVOKED BLADDER COMPLIANCE ASSOCIATED WITH HIGH URGENCY BOTHER IN A SUBSET OF WOMEN ≥50 YEARS OLD USING ULTRASOUND URODYNAMICS Michael Shields, Isabelle Pummill, Adam Vossenberg, Margaret Lefebvre, Christopher Keshishian, Julia Smolen, Sarah Kodama, Ria Khandpur, Jared Dunlap, Mina Ghatas, Linda Burkett, Lauren Siff, Ashley Carroll, Adam P. Klausner, and John E. Speich Michael ShieldsMichael Shields , Isabelle PummillIsabelle Pummill , Adam VossenbergAdam Vossenberg , Margaret LefebvreMargaret Lefebvre , Christopher KeshishianChristopher Keshishian , Julia SmolenJulia Smolen , Sarah KodamaSarah Kodama , Ria KhandpurRia Khandpur , Jared DunlapJared Dunlap , Mina GhatasMina Ghatas , Linda BurkettLinda Burkett , Lauren SiffLauren Siff , Ashley CarrollAshley Carroll , Adam P. KlausnerAdam P. Klausner , and John E. SpeichJohn E. Speich View All Author Informationhttps://doi.org/10.1097/01.JU.0001008672.83391.ed.01AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Lower urinary tract symptoms can be caused by altered bladder compliance, which is calculated during urodynamics testing (UDT) as Δvolume/Δpressure. A novel "provoked compliance" calculation may be used to assess the bladder's response to compression. The objective of this study was to quantify provoked compliance in response to bladder compressions using ultrasound (US) – UDT. METHODS: Adult patients undergoing clinically indicated UDT were enrolled. Standard compliance (ΔV/ΔP), demographics, and ICIq-OAB surveys were recorded. Provoked compliance testing was initiated by pausing the pump at 50% capacity (based on 3-day void diary). A transverse US image was captured, serving as a baseline. The bladder was then compressed by the US probe to roughly half of the baseline anterior-posterior diameter for 5 seconds followed by a 5 second pause. This process was repeated 5x with transverse US images being captured during each compression and pause. ImageJ circularity function was utilized to calculate circularity by manually tracing the bladder wall in each captured image. Provoked compliance (Δcircularity/Δpressure) was then calculated by averaging circularity and pressure data across points of max compression. RESULTS: In data analyzed from 44 participants, there was significant association between age and increased provoked compliance, particularly with patients ≥50 years old compared to younger patients (p0.0275 cm-H2O-1 in 10/22 (45.5%) participants ≥50 years old compared to 0/12 (0%) in patients 0.0275 cm-H2O-1) compared to bother scores0.05). CONCLUSIONS: Higher provoked compliance (floppier bladders) during bladder compressions was seen in patients≥50 years old and those with increased bothersome urgency. Additional investigation is required to determine association with OAB and other forms of voiding dysfunction. Download PPT Source of Funding: NIH R01DK101719, NSF REU 1852116, VCU School of Medicine Summer Research Fellowship © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e300 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Michael Shields More articles by this author Isabelle Pummill More articles by this author Adam Vossenberg More articles by this author Margaret Lefebvre More articles by this author Christopher Keshishian More articles by this author Julia Smolen More articles by this author Sarah Kodama More articles by this author Ria Khandpur More articles by this author Jared Dunlap More articles by this author Mina Ghatas More articles by this author Linda Burkett More articles by this author Lauren Siff More articles by this author Ashley Carroll More articles by this author Adam P. Klausner More articles by this author John E. Speich More articles by this author Expand All Advertisement PDF downloadLoading ...