WCN24-1037 Minimal change glomerulonephritis steroid-dependent nephrotic syndrome treated with Rituximab

Minimal lesion glomerulonephritis (MCD) represents approximately 15% of adult nephrotic syndromes. Although the exact etiology of MCD remains unknown, the activation of the immune system appears to play an important role in the pathogenesis. MCD is generally considered to be self-limiting with a benign course and an extremely low risk of progression to end stage renal disease. However, in adults the clinical manifestations are more severe. New approaches have been adopted in an attempt to limit nephrotic syndrome in adults with MCD.