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Acute kidney injury (AKI) resulting in kidney replacement therapy (KRT) is rising among critically ill adults. Long-term KRT and critical illness are independently linked to acute (i.e., delirium) and prolonged cognitive impairment and structural brain pathology. Poor regional cerebral oxygenation (rSO2) may be a contributing factor. This study sought to determine whether undertaking a longitudinal study of critically ill patients initiated on KRT was feasible. We aimed to identify barriers to enrolment and data collection, to design mitigation strategies for a future study exploring the neurological issues facing this cohort.
Jawa et al. (Mon,) studied this question.