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IgAN is the most common cause of primary glomerulonephritis. Generally, 30% of IgAN patients progress slowly to ESKD. Disease progression and prognosis of IgAN are mainly associated with clinical factors such as proteinuria, serum creatinine and pathological features including glomerular sclerosis, interstitial fibrosis and tubular atrophy. Many clinicians should make effort to minimize progression of IgAN through identifying risk factors associated with the progression of IgAN. Therefore, it is important for nephrologists to take a clinical approach through correlation analysis of various factors, including clinical or pathological factors of IgAN.
Jung et al. (Mon,) studied this question.
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