March 7, 2024Open Access

Cryptotanshinone inhibits PFK-mediated aerobic glycolysis by activating AMPK pathway leading to blockade of cutaneous melanoma

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Abstract

Cutaneous melanoma is a kind of skin malignancy with low morbidity but high mortality. Cryptotanshinone (CPT), an important component of salvia miltiorrhiza has potent anti-tumor activity and also indicates therapeutic effect on dermatosis. So we thought that CPT maybe a potential agent for therapy of cutaneous melanoma.

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Chen et al. (Thu,) studied this question.

synapsesocial.com/papers/68e7542bb6db6435876cc02f https://doi.org/https://doi.org/10.1186/s13020-024-00913-1

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