Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia and Correlation Between Platelet Count in PRP With Clinical and Trichoscopic Improvement.

Background: Androgenetic alopecia (AGA) is the most common form of patterned hair loss in males. All the available treatment options have limited clinical response. Platelet rich plasma (PRP) is one of the new promising treatment modalities in AGA and there is limited data correlating platelet count in PRP with clinical as well as trichoscopic response. Aims And Objectives: 1. To evaluate the efcacy of PRP in AGA. 2. To nd correlation between platelet count in PRP with clinical and trichoscopic response. Materials And Methods: Thirty male patients of AGA were enrolled. Every patient was given 3 sittings of PRP once a month for 3 consecutive months. Platelet count in PRP was done by improved Neubauer chamber at every sitting. Patients were followed up every 4 weekly for 24 weeks. Assessment of patients was done using global photography and trichoscopically by calculating hair density, hair diameter and terminal: vellus hair ratio (T:V ratio). Objective grading of response was done at 24 weeks. Patient satisfaction scores were calculated using visual analog scale (VAS) at 12 and 24 weeks. Statistically signicant improvement in mean hair density, hair diameter and T:V r Results: atio were seen with PRP. Patients with mean platelet count of 12.84±2.35 lacs in PRP had better improvement in trichoscopic parameters compared to cases having platelet count in PRP above or below this range. PRP therapy can be an effective therapy in the management of AGA and by Conclusion: means of proper centrifugation technique, optimum platelet count in PRP can be obtained which enhances the treatment outcome.