Skin cancer, in particular melanoma, is still one of the most significant contributing factors to cancer-related deaths globally, indicating the urgency of reliable diagnostic tools. Early discovery of skin lesions can radically increase patient survival rates, but manual diagnosis is not an easy task, and it is time-consuming as well. This paper uses Quantum Convolutional Neural Networks (QCNN), a hybrid quantum-classical model for the skin lesion classification task as being benign or malignant. The model intertwines quantum feature extraction using an amplitude encoding and parameterized quantum circuit with classical convolutional neural network (CNN) layers analyzing spatial features. Advanced pre-processing techniques and Synthetic Minority Over-sampling Techniques (SMOTE) address the class imbalance, as federated learning ensures decentralized nodes’ privacy-preserving training. The explainability of the model predictions is heightened through Quantum SHAP (Shapley Additive Explanations) and Gradient-Weighted Class Activation Mapping (Grad-CAM). This work evaluates QCNN on the Melanoma Skin Cancer Dataset of 10,600 images, achieving 96.87% training accuracy and a validation accuracy of 85% while surpassing classical benchmarks in accuracy, efficiency, and robustness. Therefore, this quantum-classical model has highlighted potential applications of medical image diagnostics through quantum-classical models
Ravi Dandu (Wed,) studied this question.