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This research examines the role of iron-sulfur-oxygen interplay in iron flux and DNA safeguarding.

December 10, 2025

The Iron-Thiol-Oxygen Nexus for Iron Flux from Bare and Ferritin-caged Mineral and Safeguarding DNA: Impact of Thiol Structure and Protein Coat

Key Points

This research examines the role of iron-sulfur-oxygen interplay in iron flux and DNA safeguarding.
Analysis of iron flux mechanisms from various sources
Investigation of thiol structure effects
Assessment of protein coat implications
Identified key interactions between iron and sulfur in regulating iron flux
Highlighted the importance of redox regulation for DNA stability

Abstract

The interplay between iron-sulfur-oxygen underpins the redox regulation of iron across biological and geochemical systems. Prior to the Great Oxygenation Event (GOE), sulfur fostered a reducing environment essential for Fe2+...

The Iron-Thiol-Oxygen Nexus for Iron Flux from Bare and Ferritin-caged Mineral and Safeguarding DNA: Impact of Thiol Structure and Protein Coat

Key Points

Abstract

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