Optimal blood pressure (BP) management following endovascular treatment (EVT) for acute ischemic stroke (AIS) secondary to intracranial large vessel occlusion remains unestablished. The randomized HOPE trial (Hemodynamic Optimization of Cerebral Perfusion after Successful Endovascular Therapy in Patients with Acute Ischemic Stroke) ( NCT04892511 ) seeks to determine if a strategy of hemodynamic optimization using different systolic BP targets, tailored to the degree of final recanalization, is superior to standard BP management in improving functional outcomes for these patients. This document outlines the final Statistical Analysis Plan (SAP) for the trial. This plan will be executed after the last follow-up is complete and the dataset has been locked.
Camps‐Renom et al. (Wed,) studied this question.
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