Crab-shape C2-symmetric chiral Tpy-bisulidine ligands: design, synthesis and application in diversity-oriented asymmetric catalysis

Key Points

• The research aims to design and synthesize new chiral bisulidine ligands for use in asymmetric catalysis.
• Utilized crab-shaped C2-symmetrical architecture for ligand design.
• Synthetized chiral Tpy-bisulidine ligands through novel methods.
• Tested ligands in diverse asymmetric catalysis reactions.
• New ligands showed enhanced coordination with metal ions.
• Achieved improved yields in asymmetric reactions compared to conventional ligands.