Characterizing the structure of a p -aminosalicylic acid and nicotinamide drug cocrystal via terahertz spectroscopy | Synapse
January 25, 2026
Characterizing the structure of a p -aminosalicylic acid and nicotinamide drug cocrystal via terahertz spectroscopy
Key Points
This research aims to analyze the structure of a drug cocrystal formed by aminosalicylic acid and nicotinamide.
Characterization of the cocrystal using terahertz spectroscopy
Application of EDA-FF methods for structure investigation
Incorporation of ESP methods to enhance analysis
Successful characterization of the cocrystal structure using terahertz spectroscopy
Identification of interactions between aminosalicylic acid and nicotinamide
Demonstration of terahertz spectroscopy's effectiveness in pharmaceutical analysis
Abstract
Terahertz spectroscopy was used to characterize the drug cocrystal of aminosalicylic acid and nicotinamide, combined with EDA-FF and ESP methods to investigate the structure of the cocrystal system.