Organ-specific autoimmunity in primary Sjögren’s disease

Key Points

• This research aims to explore the prevalence and implications of organ-specific autoimmunity (OSA) in primary Sjögren’s disease (SjD).
• Assessment of the prevalence of OSA in patients diagnosed with primary Sjögren’s disease.
• Analysis of disease activity levels in relation to OSA.
• Examination of types of endocrine involvement in OSA cases.
• One-third of patients with primary Sjögren’s disease exhibited organ-specific autoimmunity.
• Endocrine involvement was the most commonly observed type of OSA.
• OSA was found to occur independently of overall disease activity.