The study was aimed to determine the efficacy of platelet rich fibrin (PRF), Ozonated olive oil and BlueM Gel application on early wound healing following gingivectomy/gingivoplasty procedures. Method and materials: In this split-mouth study gingivectomy/gingivoplasty procedures performed on 5 patients. The postoperative PRF, Ozonated olive oil and BlueM gel applied areas were compared with control group. The clinical parameters were measured such as: plaque index, gingival index, periodontal probing depth and bleeding on probing at baseline, after IPT Whereas, VAS, LTH and H2O2 showed significant differences on group1 and group3 showed better results on postoperative days 8, 15 & 30. Conclusion: PRF releases various growth factors and not causes any side effects. Other side ozonated olive oil has antioxidant properties as well as accelerates wound healing, reduced postoperative pain and faster wound healing.
Nath et al. (Sat,) studied this question.