Ayurveda describes Lasika, a viscous fluid located between Tvak (skin) and Māṃsa (muscle), classified as an Upadhātu of Rasa Dhātu.3 Lasikā plays a crucial role in tissue lubrication, nourishment, immune defense, and the pathogenesis of diseases such as Kuṣṭha and Śotha.4 Parallel to this modern discovery, The interstitium has recently been proposed as a distinct anatomical entity characterized by a widespread network of fluid-filled spaces supported by collagen and elastin fibers.1 Once regarded merely as passive connective tissue, it is now recognized for its active roles in mechanical cushioning, fluid transport, immune surveillance, tissue repair, and disease propagation.2 This integrative review correlates modern anatomical findings on the interstitium with classical Ayurvedic descriptions of Lasikā.4 The convergence of these concepts highlights a shared understanding of interstitial fluid dynamics and underscores the relevance of integrative anatomy in explaining inflammation, edema, immune dysfunction, and chronic disease.
2Dr. Swapna Kumary *1Dr. Sushma H. N. (Sun,) studied this question.