Abstract To evaluate the effects on the bonding interface and remineralization potential of a self-etch adhesive containing 10% (w/v) 45S5 bioactive glass (BAG) in sound dentin (SD) and artificially demineralized dentin (ADD). Sound third molars were selected and stored in 0.01% thymol solution, and part of them was subjected to a pH-cycling protocol to induce controlled demineralization. The experimental groups were: SD, ADD, BAG + SD, and BAG + ADD. Microtensile bond strength (n = 8) was assessed after 24 h and six months. Nanoleakage (n = 3), micropermeability (n = 3), Knoop microhardness (n = 3 after 24 h and three months), and FT-IR spectroscopy (n = 3 immediately and after 30 days) were also performed. All specimens were stored in artificial saliva at 37 °C with monthly renewal. Data were analyzed using ANOVA and Tukey’s test (p < 0.05). The BAG + ADD group maintained bond strength after 6 months (p = 0.887). BAG reduced nanoleakage in both SD and ADD. Micropermeability showed no fluorescein uptake in SD, and reduced absorption in ADD when treated with BAG. After 3 months, BAG + ADD significantly increased microhardness at all tested depths, while BAG + SD showed improvements at 70 µm and 100 µm (p = 0.006 and p = 0.015, respectively) FT-IR analysis showed phosphate and carbonate bands in BAG-containing adhesives, with increased definition after 30 days, indicating time-dependent ion release and apatite maturation. Incorporation of BAG into a self-etch adhesive (Clearfil SE Bond) preserved long-term bond strength, enhanced dentin microhardness, promoted mineral precipitation at the adhesive interface, and improved hybrid layer, sealing—particularly in artificially demineralized dentin.
Mota et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: